Frequently asked questions about the malaria vaccine decision-making framework
What is the malaria vaccine decision-making framework?
It is a tool to aid in decisions related to malaria vaccine introduction. The framework was developed through a collaborative process involving several African countries and their international partners.
How is the tool expected to facilitate decisions around malaria vaccines?
The tool outlines the key data that decision-makers will need, a timeframe for getting the data, and the processes that need to be in place in order to make informed decisions on the appropriate use of a malaria vaccine as one becomes available.
Why is there a need for this kind of framework?
The framework addresses the unfortunate delay that has always existed between the availability of a lifesaving intervention—such as a vaccine—and its actual use in Africa and other developing regions. Slow decision-making and a lack of preparation have contributed to these delays. The framework helps countries and their partners to lay the groundwork for possible vaccine use.
How does the framework address the time lag between vaccine availability and use?
If countries apply the framework, decision-makers will have the data to determine—within one to three years of a vaccine being licensed—the appropriate role for a malaria vaccine in their country.
What kinds of data do countries need in order to decide on vaccine use?
Countries have identified a range of critical information needed to support decision-making, including the national malaria disease burden, the impact of other malaria strategies, and the quality and safety of a future vaccine.
Why is there a need to begin planning for malaria vaccine use?
The world has never been closer to having a malaria vaccine. More than 40 malaria vaccines are moving through the development process, and 16 of these are in clinical trials. The vaccine that is furthest along requires several more years of clinical investigation; however, if all goes well, this vaccine candidate could be submitted for licensing as early as 2011.
