- New interventions, including vaccines, needed to prevent disease and accelerate elimination.
- Biological feasibility, for multiple vaccine approaches, has been demonstrated.
- Identification of biomarkers of protection needed to further accelerate progress.
- Building on success of RTS,S is a leading next-generation vaccine development strategy.
- Heavy reliance on public and philanthropic funding expected to continue.
Despite recent progress in reducing deaths attributable to malaria, the disease continues to claim approximately 500,000 lives per year and is associated with approximately 200 million infections. New tools, including safe and effective vaccines, are needed to ensure that the gains of the last 15 years are leveraged toward achieving the ultimate goal of malaria parasite eradication.