The aim of this collaboration is to conduct a thorough antibody repertoire transcriptome analysis on samples from RTS,S/AS01B immunized subjects, using Atreca’s Immune Repertoire Capture™ Technology (IRC™).  By investigating sequences from paired heavy and light chain immunoglobulins, variable regions and CDR data sets, this project focuses on deepening our understanding of B cell repertoires and their evolution post-vaccination. Importantly, the association between B cell repertoires and vaccine efficacy will be assessed.