Meaningful gains against malaria have been made with interventions such as bed nets, indoor residual spraying, anti-malarial drugs, and diagnostic tools. Even as these efforts to control and eliminate malaria in some settings continue, the international community has set its sights on the long-term goal of eradicating the disease altogether. Key to eradication will be the ability to break the cycle of transmission of the malaria parasite between its human and mosquito hosts—a challenge faced by developers working on drugs, insecticides, and vaccines for malaria. A vaccine with the ability to prevent transmission of the parasite that causes malaria would be a critical tool for achieving the long-term goal of malaria eradication.
20 Apr 2016